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Personal Assessment

The Role of Glutathione in Parkinson’s Symptoms

Do you know anyone who suffers from symptoms or difficulties commonly associated with  Parkinson’s? If so we have some good news, you may want to share with them.

(These symptoms can include tremors, stiffness in arms or legs, difficulty rising from a chair, accompanied by one or more of the following: Stooped posture, reduced blinking or facial expression, smaller handwriting, shuffling, anxiety, memory problems, sleep disturbances, incontinence, muscle cramps, pain numbness or tingling, soft or monotone voice, difficulty swallowing.)

What is glutathione?

Glutathione (GSH) is a tripeptide antioxidant created by and for our body by 3 amino acids (building blocks for proteins) glutamate, cysteine, and glycine. Having been the subject or more than a thousand studies, GSH is perhaps the most studied compound in the human body.  This king of the antioxidants plays a central role in protecting cells from oxidative stress, toxic compounds and inflammation. It also plays an important role in energy production and maintaining our immune system.

Disclaimer Note:

Nutrition and supplement companies in the U.S. are not allowed to claim that their products treat, cure, prevent, or diagnose any disease. This is the FDA’s core restriction, and violating it can cause a product to be removed from the market. Moreover, we are not aware of any product containing glutathione, preventing, treating or “curing,” ANY medical condition including Parkinson’s. So in talking with others about glutathione or any other products featured on this website, please do not imply they can prevent, treat or cure such. As there really are no good studies currently that prove such.

What we are talking about here are symptoms and inabilities not any disease, or medical conditions per se. A good analogy might be arthritis and aspirin. An aspirin or two may help improve mobility with reduced pain for a period of time, but it certainly does not prevent, treat nor cure the underlying pathology or ailment, i.e. arthritis itself.

Glutathione and Symptom Relief

Last week we were informed of a retired attorney who developed a tremor and other Parkinson’s like symptoms ten years ago. But after swishing with a new form of glutathione, daily for a week or so, he reported his tremor’s had reduced significantly. In fact on some days he noted they’d all but vanished. And his wife noted his verbal fluency had improved as well.

This report reinforced previous accounts from other’s and family members, who’ve reported that after taking this for a period of time their mood had improved, speech came easier, their ability to get around was much better.  One individual in his early 70’s, who had experienced recent significant decline, even used the work “amazing,” to describe his improved muscle and limb control.

Something significant seems to be happening here, as an estimated 20,000 people throughout the world are now taking this form of glutathione to address the above noted conditions, associated with oxidative stress, and inflammation.

So why is it that people with Parkinson’s like symptoms seem to be having such remarkable results after taking this product.  Our AI CoPilot research assistant provided the following insights.

⭐ “One of the earliest and most reproducible biochemical abnormalities in Parkinson’s disease is a drop in glutathione (GSH) in the substantia nigra the brain region most affected by the disease.

Researchers have found:

  • 40–60% depletion of reduced glutathione (GSH) in the substantia nigra of people with Parkinson’s
  • This depletion appears before major dopamine loss
  • It is considered an early marker of oxidative stress in the disease
  • Low GSH is linked to mitochondrial [cellular energy generator] dysfunction, which is central to Parkinson’s pathology.

This pattern has been confirmed in multiple post‑mortem and imaging studies.

⭐ Why glutathione matters in Parkinson’s

Glutathione is the brain’s primary antioxidant, and the substantia nigra is especially vulnerable to oxidative stress because:

  • It uses a lot of oxygen
  • It contains high iron levels (which generate free radicals [and oxidative stress])
  • Dopamine metabolism itself produces oxidative byproducts

When glutathione levels fall, neurons lose their ability to neutralize oxidative stress, which contributes to:

  • Mitochondrial damage
  • Dopaminergic neuron death
  • Progression of Parkinson’s symptoms

⭐ Is low glutathione a cause or a consequence?

Researchers still debate this, but the evidence suggests:

  • Glutathione depletion happens early, possibly before major neuron loss
  • It may be a trigger for the oxidative stress cascade
  • It is not simply a byproduct of cell death

So glutathione depletion is considered a key part of the disease process.

⭐ Bottom line

  • Yes — low glutathione is extremely common in Parkinson’s disease.
  • It is one of the earliest biochemical changes in the substantia nigra.
  • It contributes to oxidative stress and mitochondrial dysfunction, both central to Parkinson’s.
  • Boosting glutathione is biologically promising, but not yet proven as a disease‑modifying therapy in humans.

Here is a link to the site of one of the top Neurologists in the world, talking about the role of glutathione in the brain. https://drperlmutter.com/glutathione-powerful-brain-protection-copy/

The Problem with Glutathione

A major problem for glutathione therapy has been figuring out how best to increase GSH levels in the body, since it’s made in the body, when taken orally it’s typically broken down and washed out in the gut. And taking it via IV’s can become quite expensive or is not often enough, to maintain needed levels throughout the week. That’s where the Neumi Nutriswish excels.
To learn more about it’s unique delivery system click here, and scroll down to The Neumi Breakthrough. The name of this product again is Nutriswish.  

If you or someone you know would like to try this…

 If you know someone who is a Neumi affiliate please get back in touch with them to make a purchase. If you do not know anyone in the Neumi family, click here and select Nutriswish in the blue bottle.

 Typically, the dose is 2 capfuls per day, swished for 1-5 minutes. Best taken first thing in the morning, or just before bed. (It usually helps improve quality of sleep.) Generally the longer one swishes the more that’s absorbed. For optimal effect as quick as possible they suggest taking a serving only once the first day. (To make sure there are no adverse reactions – though there seldom is.)  Then twice the second, 3 times the 3rd day, etc., and increase that up to 5 servings (2 caps = 1 serving) per day.

If after taking at least 3 servings for 3 days, your symptoms have not diminished, or if you have any questions or concerns call our helpline at (801) 529-8238 to discuss options, or to report progress.  We’d like to hear how this works for you or others, and there are other nutrients, we’d be glad to share, that might make this even more effective, depending on your concerns.

Spring is coming, and hopefully with it more significant improvements!
God bless!

David R. Larsen, MFHD
Director of Education
American Brain Council 

 

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